Labeling Stem Cells with a New Hybrid Bismuth/Carbon Nanotube Contrast Agent for X-Ray Imaging

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dc.citation.articleNumber2183051
dc.citation.journalTitleContrast Media & Molecular Imaging
dc.citation.volumeNumber2019
dc.contributor.authorHernández-Rivera, Mayra
dc.contributor.authorCho, Stephen Y.
dc.contributor.authorMoghaddam, Sakineh E.
dc.contributor.authorCheong, Benjamin Y.
dc.contributor.authorCabreira-Hansen, Maria da Graça
dc.contributor.authorWillerson, James T.
dc.contributor.authorPerin, Emerson C.
dc.contributor.authorWilson, Lon J.
dc.date.accessioned2019-09-17T17:11:45Z
dc.date.available2019-09-17T17:11:45Z
dc.date.issued2019
dc.description.abstractThe poor retention and survival of cells after transplantation to solid tissue represent a major obstacle for the effectiveness of stem cell-based therapies. The ability to track stem cells in vivo can lead to a better understanding of the biodistribution of transplanted cells, in addition to improving the analysis of stem cell therapies’ outcomes. Here, we described the use of a carbon nanotube-based contrast agent (CA) for X-ray computed tomography (CT) imaging as an intracellular CA to label bone marrow-derived mesenchymal stem cells (MSCs). Porcine MSCs were labeled without observed cytotoxicity. The CA consists of a hybrid material containing ultra-short single-walled carbon nanotubes (20–80 nm in length, US-tubes) and Bi(III) oxo-salicylate clusters which contain four Bi3+ ions per cluster (Bi4C). The CA is thus abbreviated as Bi4C@US-tubes.
dc.identifier.citationHernández-Rivera, Mayra, Cho, Stephen Y., Moghaddam, Sakineh E., et al.. "Labeling Stem Cells with a New Hybrid Bismuth/Carbon Nanotube Contrast Agent for X-Ray Imaging." <i>Contrast Media & Molecular Imaging,</i> 2019, (2019) Hindawi: https://doi.org/10.1155/2019/2183051.
dc.identifier.digital2183051
dc.identifier.doihttps://doi.org/10.1155/2019/2183051
dc.identifier.urihttps://hdl.handle.net/1911/107411
dc.language.isoeng
dc.publisherHindawi
dc.rightsThis is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleLabeling Stem Cells with a New Hybrid Bismuth/Carbon Nanotube Contrast Agent for X-Ray Imaging
dc.typeJournal article
dc.type.dcmiText
dc.type.publicationpublisher version
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