Labeling Stem Cells with a New Hybrid Bismuth/Carbon Nanotube Contrast Agent for X-Ray Imaging

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dc.citation.articleNumber2183051en_US
dc.citation.journalTitleContrast Media & Molecular Imagingen_US
dc.citation.volumeNumber2019en_US
dc.contributor.authorHernández-Rivera, Mayraen_US
dc.contributor.authorCho, Stephen Y.en_US
dc.contributor.authorMoghaddam, Sakineh E.en_US
dc.contributor.authorCheong, Benjamin Y.en_US
dc.contributor.authorCabreira-Hansen, Maria da Graçaen_US
dc.contributor.authorWillerson, James T.en_US
dc.contributor.authorPerin, Emerson C.en_US
dc.contributor.authorWilson, Lon J.en_US
dc.date.accessioned2019-09-17T17:11:45Zen_US
dc.date.available2019-09-17T17:11:45Zen_US
dc.date.issued2019en_US
dc.description.abstractThe poor retention and survival of cells after transplantation to solid tissue represent a major obstacle for the effectiveness of stem cell-based therapies. The ability to track stem cells in vivo can lead to a better understanding of the biodistribution of transplanted cells, in addition to improving the analysis of stem cell therapies’ outcomes. Here, we described the use of a carbon nanotube-based contrast agent (CA) for X-ray computed tomography (CT) imaging as an intracellular CA to label bone marrow-derived mesenchymal stem cells (MSCs). Porcine MSCs were labeled without observed cytotoxicity. The CA consists of a hybrid material containing ultra-short single-walled carbon nanotubes (20–80 nm in length, US-tubes) and Bi(III) oxo-salicylate clusters which contain four Bi3+ ions per cluster (Bi4C). The CA is thus abbreviated as Bi4C@US-tubes.en_US
dc.identifier.citationHernández-Rivera, Mayra, Cho, Stephen Y., Moghaddam, Sakineh E., et al.. "Labeling Stem Cells with a New Hybrid Bismuth/Carbon Nanotube Contrast Agent for X-Ray Imaging." <i>Contrast Media & Molecular Imaging,</i> 2019, (2019) Hindawi: https://doi.org/10.1155/2019/2183051.en_US
dc.identifier.digital2183051en_US
dc.identifier.doihttps://doi.org/10.1155/2019/2183051en_US
dc.identifier.urihttps://hdl.handle.net/1911/107411en_US
dc.language.isoengen_US
dc.publisherHindawien_US
dc.rightsThis is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_US
dc.titleLabeling Stem Cells with a New Hybrid Bismuth/Carbon Nanotube Contrast Agent for X-Ray Imagingen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpublisher versionen_US
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