In vivo vibrometry inside the apex of the mouse cochlea using spectral domain optical coherence tomography

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dc.citation.issueNumber2en_US
dc.citation.journalTitleJournal of Biomedical Optics Expressen_US
dc.citation.volumeNumber4en_US
dc.contributor.authorGao, Simon S.en_US
dc.contributor.authorRaphael, Patrick D.en_US
dc.contributor.authorWang, Rosalieen_US
dc.contributor.authorPark, Jesungen_US
dc.contributor.authorXia, Anpingen_US
dc.contributor.authorApplegate, Brian E.en_US
dc.contributor.authorOghalai, John S.en_US
dc.date.accessioned2013-04-29T18:56:22Zen_US
dc.date.available2013-04-29T18:56:22Zen_US
dc.date.issued2013en_US
dc.description.abstractSound transduction within the auditory portion of the inner ear, the cochlea, is a complex nonlinear process. The study of cochlear mechanics in large rodents has provided important insights into cochlear function. However, technological and experimental limitations have restricted studies in mice due to their smaller cochlea. These challenges are important to overcome because of the wide variety of transgenic mouse strains with hearing loss mutations that are available for study. To accomplish this goal, we used spectral domain optical coherence tomography to visualize and measure sound-induced vibrations of intracochlear tissues. We present, to our knowledge, the first vibration measurements from the apex of an unopened mouse cochlea.en_US
dc.embargo.termsnoneen_US
dc.identifier.citationGao, Simon S., Raphael, Patrick D., Wang, Rosalie, et al.. "In vivo vibrometry inside the apex of the mouse cochlea using spectral domain optical coherence tomography." <i>Journal of Biomedical Optics Express,</i> 4, no. 2 (2013) Optical Society of America: http://dx.doi.org/10.1364/BOE.4.000230.en_US
dc.identifier.doihttp://dx.doi.org/10.1364/BOE.4.000230en_US
dc.identifier.urihttps://hdl.handle.net/1911/71011en_US
dc.language.isoengen_US
dc.publisherOptical Society of Americaen_US
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.en_US
dc.titleIn vivo vibrometry inside the apex of the mouse cochlea using spectral domain optical coherence tomographyen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpublisher versionen_US
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