Method, apparatus, and computer-readable medium for predicting a hybridization rate constant of a first sequence

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dc.contributor.assigneeRice Universityen_US
dc.contributor.assigneeWilliam Marsh Rice Universityen_US
dc.contributor.publisherUnited States Patent and Trademark Officeen_US
dc.creatorZhang, Xuemengen_US
dc.creatorFang, Zhengen_US
dc.creatorWu, Ruojiaen_US
dc.creatorDuan, Weien_US
dc.creatorZhang, Daviden_US
dc.date.accessioned2022-11-01T15:44:54Zen_US
dc.date.available2022-11-01T15:44:54Zen_US
dc.date.filed2017-06-07en_US
dc.date.issued2022-10-18en_US
dc.description.abstractEmbodiments of methods, systems, and tangible non-transitory computer readable medium having instructions are presented. A method includes calculating a plurality of feature values for a number of bioinformatic features of the desired hybridization reaction; and calculating distances between the plurality of feature values and corresponding database rate constant values stored in a database, the database comprising a plurality of hybridization reactions having known rate constants. The method additionally includes calculating a weighted average of a logarithm of the database rate constant values, with larger weights assigned to value instances having values lower in distance to the plurality of feature values of the desired hybridization reaction; and providing the weighted average as a predicted logarithm of the rate constant of the desired hybridization reaction.en_US
dc.digitization.specificationsThis patent information was downloaded from the US Patent and Trademark website (http://www.uspto.gov/) as image-PDFs. The PDFs were OCRed for access purposes.en_US
dc.format.extent58en_US
dc.identifier.citationZhang, Xuemeng, Fang, Zheng, Wu, Ruojia, Duan, Wei and Zhang, David, "Method, apparatus, and computer-readable medium for predicting a hybridization rate constant of a first sequence." Patent US11475979B2. issued 2022-10-18. Retrieved from <a href="https://hdl.handle.net/1911/113784">https://hdl.handle.net/1911/113784</a>.en_US
dc.identifier.patentIDUS11475979B2en_US
dc.identifier.urihttps://hdl.handle.net/1911/113784en_US
dc.language.isoengen_US
dc.language.isoEnglishen_US
dc.titleMethod, apparatus, and computer-readable medium for predicting a hybridization rate constant of a first sequenceen_US
dc.typeUtility patenten_US
dc.type.dcmiTexten_US
dc.type.genrepatentsen_US
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