Mutation of the Arabidopsis LON2 peroxisomal protease enhances pexophagy

dc.citation.firstpage518en_US
dc.citation.issueNumber3en_US
dc.citation.journalTitleAutophagyen_US
dc.citation.lastpage519en_US
dc.citation.volumeNumber10en_US
dc.contributor.authorBartel, Bonnieen_US
dc.contributor.authorFarmer, Lisa M.en_US
dc.contributor.authorRinaldi, Mauro A.en_US
dc.contributor.authorYoung, Pierce G.en_US
dc.contributor.authorDanan, Charles H.en_US
dc.contributor.authorBurkhart, Sarah E.en_US
dc.date.accessioned2018-07-10T18:32:40Zen_US
dc.date.available2018-07-10T18:32:40Zen_US
dc.date.issued2014en_US
dc.description.abstractPeroxisomes are critical organelles housing various, often oxidative, reactions. Pexophagy, the process by which peroxisomes are selectively targeted for destruction via autophagy, is characterized in yeast and mammals but had not been reported in plants. In this article, we describe how the peroxisome-related aberrations of a mutant defective in the LON2 peroxisomal protease are suppressed when autophagy is prevented by mutating any of several key autophagy-related (ATG) genes. Our results reveal that plant peroxisomes can be degraded by selective autophagy and suggest that pexophagy is accelerated when the LON2 protease is disabled.en_US
dc.identifier.citationBartel, Bonnie, Farmer, Lisa M., Rinaldi, Mauro A., et al.. "Mutation of the Arabidopsis LON2 peroxisomal protease enhances pexophagy." <i>Autophagy,</i> 10, no. 3 (2014) Landes Bioscience: 518-519. https://doi.org/10.4161/auto.27565.en_US
dc.identifier.digitalauto-10-518en_US
dc.identifier.doihttps://doi.org/10.4161/auto.27565en_US
dc.identifier.urihttps://hdl.handle.net/1911/102363en_US
dc.language.isoengen_US
dc.publisherLandes Bioscienceen_US
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.en_US
dc.subject.keywordArabidopsis thalianaen_US
dc.subject.keywordautophagyen_US
dc.subject.keywordperoxisome remodelingen_US
dc.subject.keywordperoxisomal proteaseen_US
dc.subject.keywordpexophagyen_US
dc.titleMutation of the Arabidopsis LON2 peroxisomal protease enhances pexophagyen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpublisher versionen_US
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