Mutation of the Arabidopsis LON2 peroxisomal protease enhances pexophagy

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dc.citation.firstpage518
dc.citation.issueNumber3
dc.citation.journalTitleAutophagy
dc.citation.lastpage519
dc.citation.volumeNumber10
dc.contributor.authorBartel, Bonnie
dc.contributor.authorFarmer, Lisa M.
dc.contributor.authorRinaldi, Mauro A.
dc.contributor.authorYoung, Pierce G.
dc.contributor.authorDanan, Charles H.
dc.contributor.authorBurkhart, Sarah E.
dc.date.accessioned2018-07-10T18:32:40Z
dc.date.available2018-07-10T18:32:40Z
dc.date.issued2014
dc.description.abstractPeroxisomes are critical organelles housing various, often oxidative, reactions. Pexophagy, the process by which peroxisomes are selectively targeted for destruction via autophagy, is characterized in yeast and mammals but had not been reported in plants. In this article, we describe how the peroxisome-related aberrations of a mutant defective in the LON2 peroxisomal protease are suppressed when autophagy is prevented by mutating any of several key autophagy-related (ATG) genes. Our results reveal that plant peroxisomes can be degraded by selective autophagy and suggest that pexophagy is accelerated when the LON2 protease is disabled.
dc.identifier.citationBartel, Bonnie, Farmer, Lisa M., Rinaldi, Mauro A., et al.. "Mutation of the Arabidopsis LON2 peroxisomal protease enhances pexophagy." <i>Autophagy,</i> 10, no. 3 (2014) Landes Bioscience: 518-519. https://doi.org/10.4161/auto.27565.
dc.identifier.digitalauto-10-518
dc.identifier.doihttps://doi.org/10.4161/auto.27565
dc.identifier.urihttps://hdl.handle.net/1911/102363
dc.language.isoeng
dc.publisherLandes Bioscience
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
dc.subject.keywordArabidopsis thaliana
dc.subject.keywordautophagy
dc.subject.keywordperoxisome remodeling
dc.subject.keywordperoxisomal protease
dc.subject.keywordpexophagy
dc.titleMutation of the Arabidopsis LON2 peroxisomal protease enhances pexophagy
dc.typeJournal article
dc.type.dcmiText
dc.type.publicationpublisher version
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