While concerns about the consequences of anti-Semitism, Islamophobia, and other forms of religious bias have grown in the past several years, the data available to examine these issues have been limited. This study utilizes new data from a nationally representative survey of U.S. adults featuring oversamples of key religious minority groups and an instrument dedicated to measuring the extent to which individuals experience hostility, discrimination, and violence due to their religion. Findings show that, while a sizable minority of Christian adults report such experiences, a much greater share of Muslim and Jewish adults report experiences with interpersonal hostility, organizational discrimination, and violent victimization due to their religion. Analyses show that these patterns are largely unchanged after accounting for individuals’ race and ethnicity, national origin, and other characteristics, suggesting that experiences with religious hostility are not epiphenomenal to other social locations.