Cofactor engineering for advancing chemical biotechnology

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dc.citation.firstpage994en_US
dc.citation.journalTitleCurrent Opinion in Biotechnologyen_US
dc.citation.lastpage999en_US
dc.citation.volumeNumber24en_US
dc.contributor.authorWang, Yipengen_US
dc.contributor.authorSan, Ka-Yiuen_US
dc.contributor.authorBennett, George N.en_US
dc.contributor.orgBioengineeringen_US
dc.contributor.orgBiosciencesen_US
dc.contributor.orgChemical and Biomolecular Engineeringen_US
dc.date.accessioned2014-02-14T21:19:55Zen_US
dc.date.available2014-02-14T21:19:55Zen_US
dc.date.issued2013en_US
dc.description.abstractCofactors provide redox carriers for biosynthetic reactions, catabolic reactions and act as important agents in transfer of energy for the cell. Recent advances in manipulating cofactors include culture conditions or additive alterations, genetic modification of host pathways for increased availability of desired cofactor, changes in enzyme cofactor specificity, and introduction of novel redox partners to form effective circuits for biochemical processes and biocatalysts. Genetic strategies to employ ferredoxin, NADH and NADPH most effectively in natural or novel pathways have improved yield and efficiency of large-scale processes for fuels and chemicals and have been demonstrated with a variety of microbial organisms.en_US
dc.identifier.citationWang, Yipeng, San, Ka-Yiu and Bennett, George N.. "Cofactor engineering for advancing chemical biotechnology." <i>Current Opinion in Biotechnology,</i> 24, (2013) Elsevier: 994-999. http://dx.doi.org/10.1016/j.copbio.2013.03.022.en_US
dc.identifier.doihttp://dx.doi.org/10.1016/j.copbio.2013.03.022en_US
dc.identifier.urihttps://hdl.handle.net/1911/75475en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.rightsThis is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by Elsevier.en_US
dc.titleCofactor engineering for advancing chemical biotechnologyen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpost-printen_US
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