Tissue engineering perfusable cancer models

Simple item page
dc.citation.firstpage112en_US
dc.citation.journalTitleCurrent Opinion in Chemical Engineeringen_US
dc.citation.lastpage117en_US
dc.citation.volumeNumber3en_US
dc.contributor.authorFong, E.L.en_US
dc.contributor.authorSantoro, M.en_US
dc.contributor.authorFarach-Carson, Mary C.en_US
dc.contributor.authorKasper, F.K.en_US
dc.contributor.authorMikos, A.G.en_US
dc.date.accessioned2015-03-16T16:56:10Zen_US
dc.date.available2015-03-16T16:56:10Zen_US
dc.date.issued2014en_US
dc.description.abstractThe effect of fluid flow on cancer progression is currently not well understood, highlighting the need for perfused tumor models to close this gap in knowledge. Enabling biological processes at the cellular level to be modeled with high spatiotemporal control, microfluidic tumor models have demonstrated applicability as platforms to study cell-cell interactions, effect of interstitial flow on tumor migration and the role of vascular barrier function. To account for the multi-scale nature of cancer growth and invasion, macroscale models are also necessary. The consideration of fluid dynamics within tumor models at both the micro- and macroscopic levels may greatly improve our ability to more fully mimic the tumor microenvironment.en_US
dc.identifier.citationFong, E.L., Santoro, M., Farach-Carson, Mary C., et al.. "Tissue engineering perfusable cancer models." <i>Current Opinion in Chemical Engineering,</i> 3, (2014) Elsevier: 112-117. http://dx.doi.org/10.1016/j.coche.2013.12.008.en_US
dc.identifier.doihttp://dx.doi.org/10.1016/j.coche.2013.12.008en_US
dc.identifier.urihttps://hdl.handle.net/1911/79351en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.rightsThis is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by Elsevier.en_US
dc.subject.keywordtissue engineeringen_US
dc.subject.keywordcanceren_US
dc.subject.keywordperfusionen_US
dc.subject.keywordtumor modelsen_US
dc.subject.keywordfluid flowen_US
dc.titleTissue engineering perfusable cancer modelsen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpost-printen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
nihms558905.pdf
Size:
265.6 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Faculty Publications
Biochemistry and Cell Biology Publications
Bioengineering Publications
Chemical and Biomolecular Engineering Publications