Stoichiometric tuning of nucleic acid hybridization probes by auxiliary oligonucleotide species

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dc.contributor.assigneeWilliam Marsh Rice Universityen_US
dc.contributor.publisherUnited States Patent and Trademark Officeen_US
dc.creatorZhang, David Yuen_US
dc.creatorWu, Ruojiaen_US
dc.creatorWang, Juexiaoen_US
dc.date.accessioned2024-02-02T17:44:58Zen_US
dc.date.available2024-02-02T17:44:58Zen_US
dc.date.filed2021-05-21en_US
dc.date.issued2024-01-23en_US
dc.description.abstractThis invention describes a method of controlling the hybridization yield of nucleic acid probes by adjusting the relative concentrations of auxiliary oligonucleotides to the probes and the targets. The auxiliary oligonucleotide is partially or fully complementary to either the probe or the target, and is released upon hybridization of the probe to the target.en_US
dc.digitization.specificationsThis patent information was downloaded from the US Patent and Trademark website (http://www.uspto.gov/) as image-PDFs. The PDFs were OCRed for access purposes.en_US
dc.format.extent31en_US
dc.identifier.patentIDUS11879152B2en_US
dc.identifier.urihttps://hdl.handle.net/1911/115446en_US
dc.language.isoengen_US
dc.titleStoichiometric tuning of nucleic acid hybridization probes by auxiliary oligonucleotide speciesen_US
dc.typeUtility patenten_US
dc.type.dcmiTexten_US
dc.type.genrepatentsen_US
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