Stoichiometric tuning of nucleic acid hybridization probes by auxiliary oligonucleotide species

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dc.contributor.assigneeWilliam Marsh Rice University
dc.contributor.publisherUnited States Patent and Trademark Office
dc.creatorZhang, David Yu
dc.creatorWu, Ruojia
dc.creatorWang, Juexiao
dc.date.accessioned2024-02-02T17:44:58Z
dc.date.available2024-02-02T17:44:58Z
dc.date.filed2021-05-21
dc.date.issued2024-01-23
dc.description.abstractThis invention describes a method of controlling the hybridization yield of nucleic acid probes by adjusting the relative concentrations of auxiliary oligonucleotides to the probes and the targets. The auxiliary oligonucleotide is partially or fully complementary to either the probe or the target, and is released upon hybridization of the probe to the target.
dc.digitization.specificationsThis patent information was downloaded from the US Patent and Trademark website (http://www.uspto.gov/) as image-PDFs. The PDFs were OCRed for access purposes.
dc.format.extent31
dc.identifier.patentIDUS11879152B2
dc.identifier.urihttps://hdl.handle.net/1911/115446
dc.language.isoeng
dc.titleStoichiometric tuning of nucleic acid hybridization probes by auxiliary oligonucleotide species
dc.typeUtility patent
dc.type.dcmiText
dc.type.genrepatents
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