High-resolution endomicroscopy with a spectrally encoded miniature objective

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dc.citation.firstpage1432en_US
dc.citation.issueNumber3en_US
dc.citation.journalTitleBiomedical Optics Expressen_US
dc.citation.lastpage1445en_US
dc.citation.volumeNumber10en_US
dc.contributor.authorJeon, Haminen_US
dc.contributor.authorPawlowski, Michal E.en_US
dc.contributor.authorTkaczyk, Tomasz S.en_US
dc.contributor.orgBioengineeringen_US
dc.contributor.orgElectrical and Computer Engineeringen_US
dc.date.accessioned2019-12-06T15:32:21Zen_US
dc.date.available2019-12-06T15:32:21Zen_US
dc.date.issued2019en_US
dc.description.abstractFiber bundle endomicroscopy techniques have been used for numerous minimally invasive imaging applications. However, these techniques may provide limited spatial sampling due to the limited number of imaging cores inside the fiber bundle. Here, we present a custom-fabricated miniature objective that can be coupled to a fiber bundle and can overcome the fiber bundle’s sampling threshold by utilizing the spectral encoding concept. The objective has an NA of 0.3 and an outer diameter of 2.4 mm, and can yield a maximum spatial resolution of 2 μm. The objective has been validated against a USAF resolution target and ex vivo tissue samples, and as a result yielded images with higher resolution and more details after the spectral encoding concept was employed.en_US
dc.identifier.citationJeon, Hamin, Pawlowski, Michal E. and Tkaczyk, Tomasz S.. "High-resolution endomicroscopy with a spectrally encoded miniature objective." <i>Biomedical Optics Express,</i> 10, no. 3 (2019) Optical Society of America: 1432-1445. https://doi.org/10.1364/BOE.10.001432.en_US
dc.identifier.digitalboe-10-3-1432en_US
dc.identifier.doihttps://doi.org/10.1364/BOE.10.001432en_US
dc.identifier.urihttps://hdl.handle.net/1911/107788en_US
dc.language.isoengen_US
dc.publisherOptical Society of Americaen_US
dc.rights© 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreementen_US
dc.rights.urihttps://www.osapublishing.org/library/license_v1.cfm#VOR-OAen_US
dc.titleHigh-resolution endomicroscopy with a spectrally encoded miniature objectiveen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpublisher versionen_US
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