Native NAD-dependent GAPDH replaced with NADP-dependent GAPDH plus NADK

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2014-04-29
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This invention is metabolically engineer bacterial strains that provide increased intracellular NADPH availability for the purpose of increasing the yield and productivity of NADPH-dependent compounds. In the invention, native NAD-dependent GAPDH is replaced with NADP-dependent GAPDH plus overexpressed NADK. Uses for the bacteria are also provided.

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San, Ka-Yiu, Bennett, George N. and Wang, Yipeng, "Native NAD-dependent GAPDH replaced with NADP-dependent GAPDH plus NADK." Patent US8709753B2. issued 2014-04-29. Retrieved from https://hdl.handle.net/1911/80155.

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https://hdl.handle.net/1911/80155
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