Synthesis and 3D Interconnected Nanostructured h-BN-Based Biocomposites by Low-Temperature Plasma Sintering: Bone Regeneration Applications

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dc.citation.firstpage6013en_US
dc.citation.issueNumber6en_US
dc.citation.journalTitleACS Omegaen_US
dc.citation.lastpage6021en_US
dc.citation.volumeNumber3en_US
dc.contributor.authorGautam, Chandkiramen_US
dc.contributor.authorChakravarty, Dibyenduen_US
dc.contributor.authorGautam, Amarendraen_US
dc.contributor.authorTiwary, Chandra Sekharen_US
dc.contributor.authorWoellner, Cristiano Franciscoen_US
dc.contributor.authorMishra, Vijay Kumaren_US
dc.contributor.authorAhmad, Naseeren_US
dc.contributor.authorOzden, Sehmusen_US
dc.contributor.authorJose, Sujinen_US
dc.contributor.authorBiradar, Santoshkumaren_US
dc.contributor.authorVajtai, Roberten_US
dc.contributor.authorTrivedi, Rituen_US
dc.contributor.authorGalvao, Douglas S.en_US
dc.contributor.authorAjayan, Pulickel M.en_US
dc.date.accessioned2018-08-21T16:18:45Zen_US
dc.date.available2018-08-21T16:18:45Zen_US
dc.date.issued2018en_US
dc.description.abstractRecent advances and demands in biomedical applications drive a large amount of research to synthesize easily scalable low-density, high-strength, and wear-resistant biomaterials. The chemical inertness with low density combined with high strength makes h-BN one of the promising materials for such application. In this work, three-dimensional hexagonal boron nitride (h-BN) interconnected with boron trioxide (B2O3) was prepared by easily scalable and energy efficient spark plasma sintering (SPS) process. The composite structure shows significant densification (1.6–1.9 g/cm3) and high surface area (0.97–14.5 m2/g) at an extremely low SPS temperature of 250 °C. A high compressive strength of 291 MPa with a reasonably good wear resistance was obtained for the composite structure. The formation of strong covalent bonds between h-BN and B2O3 was formulated and established by molecular dynamics simulation. The composite showed significant effect on cell viability/proliferation. It shows a high mineralized nodule formation over the control, which suggests its use as a possible osteogenic agent in bone formation.en_US
dc.identifier.citationGautam, Chandkiram, Chakravarty, Dibyendu, Gautam, Amarendra, et al.. "Synthesis and 3D Interconnected Nanostructured h-BN-Based Biocomposites by Low-Temperature Plasma Sintering: Bone Regeneration Applications." <i>ACS Omega,</i> 3, no. 6 (2018) American Chemical Society: 6013-6021. https://doi.org/10.1021/acsomega.8b00707.en_US
dc.identifier.digitalacsomega.8b00707en_US
dc.identifier.doihttps://doi.org/10.1021/acsomega.8b00707en_US
dc.identifier.urihttps://hdl.handle.net/1911/102483en_US
dc.language.isoengen_US
dc.publisherAmerican Chemical Societyen_US
dc.rightsThis is an open access article published under an ACS AuthorChoice License, which permits copying and redistribution of the article or any adaptations for non-commercial purposes.en_US
dc.rights.urihttps://pubs.acs.org/page/policy/authorchoice_termsofuse.htmlen_US
dc.titleSynthesis and 3D Interconnected Nanostructured h-BN-Based Biocomposites by Low-Temperature Plasma Sintering: Bone Regeneration Applicationsen_US
dc.typeJournal articleen_US
dc.type.dcmiTexten_US
dc.type.publicationpublisher versionen_US
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