Browsing by Author "Liu, Helen"

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    A Successive Linear Programming Approach to IMRT Optimization Problem
    (2002-12) Merritt, Michael; Zhang, Yin; Liu, Helen; Mohan, Radhe
    We propose to solve the IMRT optimization problem through a successive linear programming approach. Taking advantage of the sensitivity information in linear programming and the re-optimization ability of simplex methods, the proposed approach provides an affordable methodology to efficiently solve problems with dose-volume constraints. Preliminary computational results indicate that, compared to the standard weighted least squares approach, the new approach leads to higher tumor dosage escalation and better conformation.