A Successive Linear Programming Approach to IMRT Optimization Problem

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2002-12
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We propose to solve the IMRT optimization problem through a successive linear programming approach. Taking advantage of the sensitivity information in linear programming and the re-optimization ability of simplex methods, the proposed approach provides an affordable methodology to efficiently solve problems with dose-volume constraints. Preliminary computational results indicate that, compared to the standard weighted least squares approach, the new approach leads to higher tumor dosage escalation and better conformation.

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Merritt, Michael, Zhang, Yin, Liu, Helen, et al.. "A Successive Linear Programming Approach to IMRT Optimization Problem." (2002) https://hdl.handle.net/1911/101995.

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