Browsing by Author "Jow, Chung-Kuang"
Now showing 1 - 1 of 1
Results Per Page
Sort Options
Item Synthetic studies on ecteinascidin 743(1995) Jow, Chung-Kuang; Fukuyama, TohruSynthetic studies on ecteinascidin 743 (b), an antitumor antibiotic, are described. The key reactions include: (1) an acylimmium ion-mediated stereoselective construction of the optically pure diazobicyclo (3.3.1) nonane nucleus 6, (2) a stereocontrolled Pictet-Spengler cyclization for the formation of tetrahydroisoquinoline 2, and (3) the attempted benzylic oxidation of the pentacyclic phenol 22.(DIAGRAM, TABLE OR GRAPHIC OMITTED...PLEASE SEE DAI)