Browsing by Author "Gomel, Madeleine A."
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Item Comparing the Role of Mechanical Forces in Vascular and Valvular Calcification Progression(Frontiers, 2019) Gomel, Madeleine A.; Lee, Romi; Grande-Allen, K. Janeregulator of lysosomal function, or by inducing TFEB activation chemically. Because of its small format, rapidity, sensitivity and reproducibility, the NAG one-step cell assay is suitable for multiple procedures, including the high-throughput screening of chemical libraries to identify modulators of NAG expression, folding and activity, and the investigation of candidate molecules and constructs for applications in enzyme replacement therapy, gene therapy, and combination therapies.