A model of normal and depressed conduction in cardiac strands

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dc.contributor.advisorClark, John W., Jr.en_US
dc.creatorMurphey, Carey Richarden_US
dc.date.accessioned2009-06-04T00:12:20Zen_US
dc.date.available2009-06-04T00:12:20Zen_US
dc.date.issued1988en_US
dc.description.abstractMathematical modeling of the electrical activity of a single cardiac cell and of strands of cardiac cells are problems of fundamental interest in the area of electrophysiology. New and increasingly comprehensive data on the electrophysiological behavior of single, isolated cardiac myocytes have facilitated the development of more 'complete' models and are used here for the development of mathematical characterizations of cells exhibiting 'normal' electrophysiologic behavior as well as those exhibiting 'depressed' activity. Simulation and parameter estimation techniques are utilized to investigate model-generated single cell electrical behavior and to adjust this behavior to best fit observed responses. Suitably 'identified' models may be used in further simulations of electrical activity in linear strands of resistively coupled cardiac cells. It is hoped that together with advances in experimental methods, these methods for analysis and adjustment of model behavior will provide new and meaningful insight into the mechanisms of cardiac electrical activity.en_US
dc.format.extent125 p.en_US
dc.format.mimetypeapplication/pdfen_US
dc.identifier.callnoTHESIS E.E. 1988 MURPHEYen_US
dc.identifier.citationMurphey, Carey Richard. "A model of normal and depressed conduction in cardiac strands." (1988) Master’s Thesis, Rice University. <a href="https://hdl.handle.net/1911/13310">https://hdl.handle.net/1911/13310</a>.en_US
dc.identifier.urihttps://hdl.handle.net/1911/13310en_US
dc.language.isoengen_US
dc.rightsCopyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.en_US
dc.subjectBiomedical engineeringen_US
dc.titleA model of normal and depressed conduction in cardiac strandsen_US
dc.typeThesisen_US
dc.type.materialTexten_US
thesis.degree.departmentElectrical Engineeringen_US
thesis.degree.disciplineEngineeringen_US
thesis.degree.grantorRice Universityen_US
thesis.degree.levelMastersen_US
thesis.degree.nameMaster of Scienceen_US
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