Adaptive regularization based on noise estimation and its application to the inverse problem in electrocardiography

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dc.contributor.advisorClark, John W., Jr.
dc.creatorZhang, Fulong
dc.date.accessioned2009-06-04T08:29:36Z
dc.date.available2009-06-04T08:29:36Z
dc.date.issued1998
dc.description.abstractThe inverse problem was solved to reconstruct endocardial electrograms from cavitary electrograms measured with a noncontact multielectrode probe. Noise levels were estimated at each time instant by extrapolating noise energy from high spatial frequency components of probe potentials. Based on estimated noise and energy distribution of probe potentials, a matrix of weighting factors was derived to inversely mimic the band shape of the energy spectrum. By incorporating those weighting factors into the inverse procedure, a set of regularization parameters was derived and applied in solving the inverse problem (i.e. adaptive regularization). Adaptive regularization was tested on an experimental canine model. Both traditional uniform regularization and adaptive regularization were applied to compute endocardial electrograms during normal as well as paced rhythms. Adaptive regularization demonstrated a great improvement over uniform regularization in terms of improved correlation coefficients, reduced relative error, better estimation of activation times and localization of pacing sites.
dc.format.extent92 p.en_US
dc.format.mimetypeapplication/pdf
dc.identifier.callnoTHESIS E.E. 1998 ZHANG, F.
dc.identifier.citationZhang, Fulong. "Adaptive regularization based on noise estimation and its application to the inverse problem in electrocardiography." (1998) Master’s Thesis, Rice University. <a href="https://hdl.handle.net/1911/17227">https://hdl.handle.net/1911/17227</a>.
dc.identifier.urihttps://hdl.handle.net/1911/17227
dc.language.isoeng
dc.rightsCopyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.
dc.subjectBiomedical engineering
dc.subjectElectronics
dc.subjectElectrical engineering
dc.titleAdaptive regularization based on noise estimation and its application to the inverse problem in electrocardiography
dc.typeThesis
dc.type.materialText
thesis.degree.departmentElectrical Engineering
thesis.degree.disciplineEngineering
thesis.degree.grantorRice University
thesis.degree.levelMasters
thesis.degree.nameMaster of Science
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