A computational framework for evaluating outcomes in infant craniosynostosis reconstruction

dc.contributor.advisorGoldman, Ronen_US
dc.creatorYuan, Binhangen_US
dc.date.accessioned2017-08-02T17:52:01Zen_US
dc.date.available2017-08-02T17:52:01Zen_US
dc.date.created2016-05en_US
dc.date.issued2016-02-11en_US
dc.date.submittedMay 2016en_US
dc.date.updated2017-08-02T17:52:01Zen_US
dc.description.abstractHistorically, surgical outcomes in craniosynostosis have been evaluated by qualitative analysis, direct and indirect anthropometry, cephalometrics, and CT craniometric analysis. Three-dimensional meshes constructed from 3dMD images acquired on patients with synostosis at multiple times across the course of surgical treatment provide ideal raw data for a novel approach to 3D geometric shape analysis of surgical results. We design a automatic computational framework for evaluating and visualizing the results of infant cranial surgeries based on 3dMD images. The goal of this framework is to assist surgeons in evaluating the efficacy of their surgical techniques. Feedback from surgeons in Texas Children's Hospital confirms that this framework is a robust computational system within which surgical outcomes in synostosis can be accurately and meaningfully evaluated. We also propose an algorithm to generate normative infant cranial models from the input of 3D meshes, which are extracted from CT scans of normal infant skulls. Comparing of the head shape of an affected subject with a normal control will more clearly illustrate in what aspect the subject's head deviates from the norm. Comparing of a post-treatment subject's head shape and an age-matched control would allow assessing of a specific treatment approach or surgical technique.en_US
dc.format.mimetypeapplication/pdfen_US
dc.identifier.citationYuan, Binhang. "A computational framework for evaluating outcomes in infant craniosynostosis reconstruction." (2016) Master’s Thesis, Rice University. <a href="https://hdl.handle.net/1911/96228">https://hdl.handle.net/1911/96228</a>.en_US
dc.identifier.urihttps://hdl.handle.net/1911/96228en_US
dc.language.isoengen_US
dc.rightsCopyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.en_US
dc.subjectSurgery Evaluationen_US
dc.subjectVisualizationen_US
dc.subjectCurvatureen_US
dc.subjectNormal Vecteren_US
dc.titleA computational framework for evaluating outcomes in infant craniosynostosis reconstructionen_US
dc.typeThesisen_US
dc.type.materialTexten_US
thesis.degree.departmentComputer Scienceen_US
thesis.degree.disciplineEngineeringen_US
thesis.degree.grantorRice Universityen_US
thesis.degree.levelMastersen_US
thesis.degree.nameMaster of Scienceen_US
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