An electrodiffusion model of conduction in nerve fibers

Date
1995
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Abstract

A new membrane model for mammalian nerve fibers has been developed. The membrane model utilizes new characterizations for delayed-rectifier currents, and adds an inwardly-rectifying potassium channel as well as a sodium-potassium pump current. Fits are shown to action potential and I-V data at two different temperatures. The Nernst-Planck electrodiffusion equation was then utilized to derive a linked compartmental model of the unmyelinated mammalian nerve fiber with lumped parameter values. The results from this unmyelinated fiber model were presented and compared to data in the literature. A myelinated nerve axon model is also developed and issues of numerical implementation are discussed.

Description
Degree
Master of Science
Type
Thesis
Keywords
Electronics, Electrical engineering, Biomedical engineering, Neurosciences, Biology, Engineering
Citation

McMahon, Michael George. "An electrodiffusion model of conduction in nerve fibers." (1995) Master’s Thesis, Rice University. https://hdl.handle.net/1911/13976.

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