Bayesian Adaptive and Interpretable Functional Regression Models

dc.contributor.advisorKowal, Danielen_US
dc.creatorGao, Yunanen_US
dc.date.accessioned2024-01-22T22:14:40Zen_US
dc.date.available2024-01-22T22:14:40Zen_US
dc.date.created2023-12en_US
dc.date.issued2023-11-28en_US
dc.date.submittedDecember 2023en_US
dc.date.updated2024-01-22T22:14:40Zen_US
dc.description.abstractScalar-on-function regression (SOFR) is a widely used tool in the medical and behavioral sciences, which elucidates the association between a scalar response and data collected repeatedly across a continuous domain. However, estimating and interpreting SOFR models pose significant challenges due to the high autocorrelation and dimensionality of functional predictors. This work presents novel estimation and inference tools for Bayesian SOFR models. Firstly, we propose a locally adaptive and highly scalable Bayesian SOFR model. By combining a B-spline basis expansion with dynamic shrinkage priors on the regression coefficient function, our model achieves more accurate point estimates and precise uncertainty quantification, particularly when capturing both smooth and rapidly-changing features. Secondly, we provide decision analysis tools for Bayesian SOFR models that extract locally constant summaries based on the posterior predictive distribution. These summaries help identify critical windows—regions in the domain of the functional covariates that predict the scalar response. Leveraging the proposed Bayesian SOFR model and decision analysis tools, we investigate the relationship between prenatal daily PM2.5 exposure and standardized 4th-grade reading test scores in a large cohort of North Carolina students. Our findings indicate that prenatal PM2.5 exposure during early and late pregnancy has the most adverse impact on the testing scores. Lastly, we extend the proposed Bayesian SOFR model and decision analysis strategy to handle multiple functional covariates, nonlinear relationships, and binary indicator response variables. Using this generalized framework, we explore the effects of prenatal temperature and PM2.5 exposure on birth weight in Michigan. Our analysis reveals that higher temperature and PM2.5 exposure are associated with lower birth weights, with higher temperature exhibiting a stronger effect than PM2.5. We provide an R package (BaiSOFR), that implements the proposed model and decision analysis strategy, along with a vignette illustrating its application on simulated data.en_US
dc.embargo.lift2024-06-01en_US
dc.embargo.terms2024-06-01en_US
dc.format.mimetypeapplication/pdfen_US
dc.identifier.citationGao, Yunan. "Bayesian Adaptive and Interpretable Functional Regression Models." (2023) PhD diss., Rice University. https://hdl.handle.net/1911/115352en_US
dc.identifier.urihttps://hdl.handle.net/1911/115352en_US
dc.language.isoengen_US
dc.rightsCopyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.en_US
dc.subjectdecision analysisen_US
dc.subjectfunctional data analysisen_US
dc.subjectnonparametric regressionen_US
dc.subjectshrinkageen_US
dc.subjectsplineen_US
dc.titleBayesian Adaptive and Interpretable Functional Regression Modelsen_US
dc.typeThesisen_US
dc.type.materialTexten_US
thesis.degree.departmentStatisticsen_US
thesis.degree.disciplineEngineeringen_US
thesis.degree.grantorRice Universityen_US
thesis.degree.levelDoctoralen_US
thesis.degree.nameDoctor of Philosophyen_US
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