Historical Perspectives on the Epidemiology of Human Chagas Disease in Texas and Recommendations for Enhanced Understanding of Clinical Chagas Disease in the Southern United States

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dc.citation.firstpagee0003981en_US
dc.contributor.authorGarcia, Melissa N.en_US
dc.contributor.authorWoc-Colburn, Lailaen_US
dc.contributor.authorAguilar, Daviden_US
dc.contributor.authorHotez, Peter J.en_US
dc.contributor.authorMurray, Kristy O.en_US
dc.contributor.orgJames A. Baker III Institute for Public Policyen_US
dc.date.accessioned2016-07-07T19:29:02Zen_US
dc.date.available2016-07-07T19:29:02Zen_US
dc.date.issued2015en_US
dc.description.abstractChagas disease (Trypanosoma cruzi infection) has recently been identified as an important neglected tropical disease in the United States. Anecdotally referred to as a “silent killer,” it leads to the development of potentially fatal cardiac disease in approximately 30% of those infected. In an attempt to better understand the potential of Chagas disease as a significant underlying cause of morbidity in Texas, we performed a historical literature review to assess disease burden. Human reports of triatomine bites and disease exposure were found to be prevalent in Texas. Despite current beliefs that Chagas disease is a recently emerging disease, we report historical references dating as far back as 1935. Both imported cases and autochthonous transmission contribute to the historical disease burden in Texas. We end by discussing the current knowledge gaps, and recommend priorities for advancing further epidemiologic studies and their policy implications.en_US
dc.identifier.citationGarcia, Melissa N., Woc-Colburn, Laila, Aguilar, David, et al.. "Historical Perspectives on the Epidemiology of Human Chagas Disease in Texas and Recommendations for Enhanced Understanding of Clinical Chagas Disease in the Southern United States." <i>PLoS Neglected Tropical Diseases,</i> 9, no. 11 (2015) Public Library of Science: e0003981. http://dx.doi.org/10.1371/journal.pntd.0003981.en_US
dc.identifier.doihttp://dx.doi.org/10.1371/journal.pntd.0003981en_US
dc.identifier.urihttps://hdl.handle.net/1911/90829en_US
dc.language.isoengen_US
dc.relation.urihttp://bakerinstitute.org/research/historical-perspectives-epidemiology-chagas-disease-texas/en_US
dc.titleHistorical Perspectives on the Epidemiology of Human Chagas Disease in Texas and Recommendations for Enhanced Understanding of Clinical Chagas Disease in the Southern United Statesen_US
dc.type.dcmiTexten_US
dc.type.publicationpublisher versionen_US
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