The energy of breathing in a nonlinear model of the human lung

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dc.contributor.advisorGhorbel, Fathi H.en_US
dc.contributor.advisorClark, John W., Jr.en_US
dc.creatorAthanasiades, Athanasiosen_US
dc.date.accessioned2009-06-04T06:53:19Zen_US
dc.date.available2009-06-04T06:53:19Zen_US
dc.date.issued1997en_US
dc.description.abstractA Lagrangian approach is used to perform an energy analysis on a nonlinear model of the human lung. Energy functions associated with the mechanics of breathing are obtained. Analytical expressions are derived for the work of breathing (WOB) and are subsequently evaluated for a typical pulmonary function laboratory test that includes tidal breathing, panting and the forced vital capacity maneuvers. The analysis successfully mimics information presented in the conventional Campbell diagram, which is often used to graphically estimate the work of breathing. In addition, it reveals dynamic aspects of muscular effort during a breathing cycle that are not immediately apparent in the Campbell diagram. Additional simulations, based on an expanded model that accounts for gas compressibility, reveal that WOB is underestimated during forceful breathing maneuvers when compressibility effects are ignored. The energy analysis provides valuable insight into the mechanics of respiration, and, in particular, the significance of individual model components.en_US
dc.format.extent62 p.en_US
dc.format.mimetypeapplication/pdfen_US
dc.identifier.callnoTHESIS M.E. 1997 ATHANASIADESen_US
dc.identifier.citationAthanasiades, Athanasios. "The energy of breathing in a nonlinear model of the human lung." (1997) Master’s Thesis, Rice University. <a href="https://hdl.handle.net/1911/17061">https://hdl.handle.net/1911/17061</a>.en_US
dc.identifier.urihttps://hdl.handle.net/1911/17061en_US
dc.language.isoengen_US
dc.rightsCopyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.en_US
dc.subjectApplied mechanicsen_US
dc.subjectPhysiologyen_US
dc.subjectBiomedical engineeringen_US
dc.titleThe energy of breathing in a nonlinear model of the human lungen_US
dc.typeThesisen_US
dc.type.materialTexten_US
thesis.degree.departmentMechanical Engineeringen_US
thesis.degree.disciplineEngineeringen_US
thesis.degree.grantorRice Universityen_US
thesis.degree.levelMastersen_US
thesis.degree.nameMaster of Scienceen_US
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