1.2 Risk-benefit analysis worksheet for biotechnology beyond conventional containment

dc.contributor.authorAbbott, Zacken_US
dc.contributor.authorFlores, Alonsoen_US
dc.contributor.authorMurray, Richarden_US
dc.date.accessioned2025-06-03T19:43:09Zen_US
dc.date.available2025-06-03T19:43:09Zen_US
dc.date.issued2025en_US
dc.descriptionThis entreaty was created as part of The Spirit of Asilomar and the Future of Biotechnology summit (February 23-26, 2025) in Pacific Grove, CA.en_US
dc.description.abstractThis report presents a structured risk-benefit analysis framework developed through discussions at the Spirit of Asilomar summit under the Biotechnologies Beyond Conventional Containment (BBCC) theme. As biotechnologies increasingly move beyond traditional laboratory and industrial confinement into open environmental applications, novel risks, ethical considerations, and societal implications arise. Recognizing the limitations of defining universal "safe design guidelines”, this report focuses instead on creating a practical, context-sensitive worksheet to guide scientists in early-stage project development. The worksheet prompts users to evaluate potential benefits—environmental, health, economic, and societal—against biological, ecological, health, regulatory, and security risks, while acknowledging the inevitability of residual risks. It encourages interdisciplinary consultation, highlighting the importance of engaging with experts and stakeholders to ensure responsible innovation. Serving as a preliminary self-assessment tool, the worksheet is designed to complement, not replace, formal regulatory processes. It aims to foster more thoughtful and transparent biotechnology design decisions and to evolve over time through broader community input.en_US
dc.identifier.citationAbbott, Z., Flores, A., & Murray, R. (2025). 1.2 Risk-benefit analysis worksheet for biotechnology beyond conventional containment. Rice University. https://doi.org/10.25611/Y8KS-DQ61en_US
dc.identifier.digitalSOA_2025.1.2_Risk-benefit_analysis_worksheet_for_biotechnology_beyond_conventional_containmenten_US
dc.identifier.doihttps://doi.org/10.25611/Y8KS-DQ61en_US
dc.identifier.orcidhttps://orcid.org/0000-0001-9859-078Xen_US
dc.identifier.orcidhttps://orcid.org/0000-0002-5785-7481en_US
dc.identifier.orcidhttps://orcid.org/0009-0006-0929-2056en_US
dc.identifier.urihttps://hdl.handle.net/1911/118548en_US
dc.language.isoengen_US
dc.publisherRice Universityen_US
dc.rightsThis work is protected by copyright and is made available here for research and educational purposes. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.en_US
dc.title1.2 Risk-benefit analysis worksheet for biotechnology beyond conventional containmenten_US
dc.typeReporten_US
dc.type.dcmiTexten_US
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