Direct Water and Fat Determination in Two-Point Dixon Imaging

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dc.contributor.advisorClark, John W., Jr.
dc.contributor.committeeMemberMa, Jingfei
dc.contributor.committeeMemberKillian, Thomas C.
dc.contributor.committeeMemberKelly, Kevin F.
dc.creatorRambow, Olen
dc.date.accessioned2013-09-16T16:35:13Z
dc.date.accessioned2013-09-16T16:35:16Z
dc.date.available2013-09-16T16:35:13Z
dc.date.available2013-09-16T16:35:16Z
dc.date.created2013-05
dc.date.issued2013-09-16
dc.date.submittedMay 2013
dc.date.updated2013-09-16T16:35:16Z
dc.description.abstractThe Dixon technique is a well-established method in magnetic resonance imaging for obtaining separate images of water and fat. Here we present a generalized solution to the two-point Dixon problem with a geometric interpretation, allowing for flexible echo times and a multi-peak fat model. By simulation and experiment, we have analyzed the dependence on the echo times of the error in the water, fat, and relative background phasor values due to both signal noise and T2* decay. Furthermore, we have demonstrated that broken symmetry due to the multi-peak nature of fat enables direct water and fat determination without phase correction, and we have quantified the reliability of this technique as a function of the echo times. The results may provide valuable guidance for selecting scan parameters to balance the objectives of optimizing fat-water identification, minimizing error in the pixel values, and minimizing total scan time.
dc.format.mimetypeapplication/pdf
dc.identifier.citationRambow, Olen. "Direct Water and Fat Determination in Two-Point Dixon Imaging." (2013) Master’s Thesis, Rice University. <a href="https://hdl.handle.net/1911/72028">https://hdl.handle.net/1911/72028</a>.
dc.identifier.slug123456789/ETD-2013-05-498
dc.identifier.urihttps://hdl.handle.net/1911/72028
dc.language.isoeng
dc.rightsCopyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.
dc.subjectMagnetic resonance imaging (MRI)
dc.subjectDixon imaging
dc.subjectMultipeak fat model
dc.subjectFat and water imaging
dc.subjectDual echo
dc.subjectFlexible echo times
dc.subjectMedical imaging
dc.titleDirect Water and Fat Determination in Two-Point Dixon Imaging
dc.typeThesis
dc.type.materialText
thesis.degree.departmentApplied Physics
thesis.degree.disciplineNatural Sciences
thesis.degree.grantorRice University
thesis.degree.levelMasters
thesis.degree.nameMaster of Science
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