Direct Water and Fat Determination in Two-Point Dixon Imaging

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dc.contributor.advisorClark, John W., Jr.en_US
dc.contributor.committeeMemberMa, Jingfeien_US
dc.contributor.committeeMemberKillian, Thomas C.en_US
dc.contributor.committeeMemberKelly, Kevin F.en_US
dc.creatorRambow, Olenen_US
dc.date.accessioned2013-09-16T16:35:13Zen_US
dc.date.accessioned2013-09-16T16:35:16Zen_US
dc.date.available2013-09-16T16:35:13Zen_US
dc.date.available2013-09-16T16:35:16Zen_US
dc.date.created2013-05en_US
dc.date.issued2013-09-16en_US
dc.date.submittedMay 2013en_US
dc.date.updated2013-09-16T16:35:16Zen_US
dc.description.abstractThe Dixon technique is a well-established method in magnetic resonance imaging for obtaining separate images of water and fat. Here we present a generalized solution to the two-point Dixon problem with a geometric interpretation, allowing for flexible echo times and a multi-peak fat model. By simulation and experiment, we have analyzed the dependence on the echo times of the error in the water, fat, and relative background phasor values due to both signal noise and T2* decay. Furthermore, we have demonstrated that broken symmetry due to the multi-peak nature of fat enables direct water and fat determination without phase correction, and we have quantified the reliability of this technique as a function of the echo times. The results may provide valuable guidance for selecting scan parameters to balance the objectives of optimizing fat-water identification, minimizing error in the pixel values, and minimizing total scan time.en_US
dc.format.mimetypeapplication/pdfen_US
dc.identifier.citationRambow, Olen. "Direct Water and Fat Determination in Two-Point Dixon Imaging." (2013) Master’s Thesis, Rice University. <a href="https://hdl.handle.net/1911/72028">https://hdl.handle.net/1911/72028</a>.en_US
dc.identifier.slug123456789/ETD-2013-05-498en_US
dc.identifier.urihttps://hdl.handle.net/1911/72028en_US
dc.language.isoengen_US
dc.rightsCopyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.en_US
dc.subjectMagnetic resonance imaging (MRI)en_US
dc.subjectDixon imagingen_US
dc.subjectMultipeak fat modelen_US
dc.subjectFat and water imagingen_US
dc.subjectDual echoen_US
dc.subjectFlexible echo timesen_US
dc.subjectMedical imagingen_US
dc.titleDirect Water and Fat Determination in Two-Point Dixon Imagingen_US
dc.typeThesisen_US
dc.type.materialTexten_US
thesis.degree.departmentApplied Physicsen_US
thesis.degree.disciplineNatural Sciencesen_US
thesis.degree.grantorRice Universityen_US
thesis.degree.levelMastersen_US
thesis.degree.nameMaster of Scienceen_US
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