Heart disease is the leading cause of death in the United States. Left ventricular assist devices (LVAD) have been shown to be effective for treating late-stage congestive heart failure as bridge to transplant, and destination therapies. Continuous flow LVADs are currently the most clinically used however, continuous flow veers away from the naturally physiological pulsatile flow of the heart and circulatory system. This causes complications including but not limited to internal bleeding, and increased chance of thrombosis and stroke. An artificial pulsatile flow can be created with a continuous flow LVAD by increasing and decreasing its speed. Synchronizing this speed changes to the heart’s rhythm will result in flow and pressure closer to the physiological norm. This thesis covers the hemodynamic response of heartbeat synchronized speed modulation in simulation, and experimentally using a Frank-Starling controlled mock circulatory loop.