Multisystem inflammatory syndrome in children (MIS-C) and the coronavirus pandemic: Current knowledge and implications for public health
dc.citation.firstpage | 484 | |
dc.citation.issueNumber | 4 | |
dc.citation.journalTitle | Journal of Infection and Public Health | |
dc.citation.lastpage | 494 | |
dc.citation.volumeNumber | 14 | |
dc.contributor.author | Rafferty, Megan S. | |
dc.contributor.author | Burrows, Hannah | |
dc.contributor.author | Joseph, Jake P. | |
dc.contributor.author | Leveille, Jennifer | |
dc.contributor.author | Nihtianova, Snejana | |
dc.contributor.author | Amirian, E. Susan | |
dc.contributor.org | Public Health & Healthcare Program, Texas Policy Lab | |
dc.date.accessioned | 2021-03-23T16:26:56Z | |
dc.date.available | 2021-03-23T16:26:56Z | |
dc.date.issued | 2021 | |
dc.description.abstract | The coronavirus disease 2019 (COVID-19) pandemic has caused widespread mortality and morbidity. Though children are largely spared from severe illness, a novel childhood hyperinflammatory syndrome presumed to be associated with and subsequent to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has emerged with potentially severe outcomes. Multisystem inflammatory disorder in children (MIS-C) most commonly affects young, school-aged children and is characterized by persistent fever, systemic hyperinflammation, and multisystem organ dysfunction. While uncommon and generally treatable, MIS-C presents potentially life-altering medical sequelae, complicated by a dearth of information regarding its etiology, pathophysiology, and long-term outcomes. The severity of MIS-C may warrant the need for increased awareness and continued COVID-19 mitigation efforts, particularly until potential factors conferring a predisposition to MIS-C can be clarified through additional research. Well-informed guidelines will be critical as the school year progresses. In this article, current knowledge on MIS-C is reviewed and the potential implications of this novel syndrome are discussed from a public health perspective. | |
dc.identifier.citation | Rafferty, Megan S., Burrows, Hannah, Joseph, Jake P., et al.. "Multisystem inflammatory syndrome in children (MIS-C) and the coronavirus pandemic: Current knowledge and implications for public health." <i>Journal of Infection and Public Health,</i> 14, no. 4 (2021) Elsevier: 484-494. https://doi.org/10.1016/j.jiph.2021.01.008. | |
dc.identifier.doi | https://doi.org/10.1016/j.jiph.2021.01.008 | |
dc.identifier.uri | https://hdl.handle.net/1911/110186 | |
dc.language.iso | eng | |
dc.publisher | Elsevier | |
dc.rights | This is an open access article under the CC BY-NC-ND license | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.subject.keyword | Multisystem inflammatory disorder in children;Pediatric inflammatory multisystem syndrome;Coronavirus;MIS-C;PIMS;COVID-19 | |
dc.title | Multisystem inflammatory syndrome in children (MIS-C) and the coronavirus pandemic: Current knowledge and implications for public health | |
dc.type | Journal article | |
dc.type.dcmi | Text | |
dc.type.publication | publisher version |
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