Optimizing Waitlist Composition from the Transplant Center's Perspective

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dc.contributor.advisorSchaefer, Andrew J
dc.creatorMildebrath, David T.K.
dc.date.accessioned2019-05-17T16:42:42Z
dc.date.available2020-12-01T06:01:10Z
dc.date.created2018-12
dc.date.issued2018-11-13
dc.date.submittedDecember 2018
dc.date.updated2019-05-17T16:42:42Z
dc.description.abstractWe present the first model to optimize patient selection for lung transplantation from the perspective of the transplant center. In 2007, the Centers for Medicare and Medicaid Services (CMS) introduced regulations designed to improve medical outcomes at transplant centers by financially penalizing transplant centers with high one-year post-transplant mortality rates. Since then, much work has focused on optimal allocation of organs within organ donation networks, but none has focused on optimizing the center-level patient mix in order to comply with CMS regulations. We introduce a chance-constrained non-linear mixed-integer programming model to maximize the number of patients who receive a transplant, while constraining the risk of penalization by the CMS. In addition, our model can be used to model dynamic pay-for-performance systems, which have seen growing popularity in the medical context. The present work may contribute to significant medical cost reduction and improve post-surgery survival rates for transplant recipients, thereby serving to keep more transplant centers open.
dc.embargo.terms2020-12-01
dc.format.mimetypeapplication/pdf
dc.identifier.citationMildebrath, David T.K.. "Optimizing Waitlist Composition from the Transplant Center's Perspective." (2018) Master’s Thesis, Rice University. <a href="https://hdl.handle.net/1911/105883">https://hdl.handle.net/1911/105883</a>.
dc.identifier.urihttps://hdl.handle.net/1911/105883
dc.language.isoeng
dc.rightsCopyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.
dc.subjectOrgan Transplantation
dc.subjectMathematical Programming
dc.subjectOperations Research
dc.titleOptimizing Waitlist Composition from the Transplant Center's Perspective
dc.typeThesis
dc.type.materialText
thesis.degree.departmentComputational and Applied Mathematics
thesis.degree.disciplineEngineering
thesis.degree.grantorRice University
thesis.degree.levelMasters
thesis.degree.nameMaster of Arts
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