Optimizing Waitlist Composition from the Transplant Center's Perspective

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dc.contributor.advisorSchaefer, Andrew Jen_US
dc.creatorMildebrath, David T.K.en_US
dc.date.accessioned2019-05-17T16:42:42Zen_US
dc.date.available2020-12-01T06:01:10Zen_US
dc.date.created2018-12en_US
dc.date.issued2018-11-13en_US
dc.date.submittedDecember 2018en_US
dc.date.updated2019-05-17T16:42:42Zen_US
dc.description.abstractWe present the first model to optimize patient selection for lung transplantation from the perspective of the transplant center. In 2007, the Centers for Medicare and Medicaid Services (CMS) introduced regulations designed to improve medical outcomes at transplant centers by financially penalizing transplant centers with high one-year post-transplant mortality rates. Since then, much work has focused on optimal allocation of organs within organ donation networks, but none has focused on optimizing the center-level patient mix in order to comply with CMS regulations. We introduce a chance-constrained non-linear mixed-integer programming model to maximize the number of patients who receive a transplant, while constraining the risk of penalization by the CMS. In addition, our model can be used to model dynamic pay-for-performance systems, which have seen growing popularity in the medical context. The present work may contribute to significant medical cost reduction and improve post-surgery survival rates for transplant recipients, thereby serving to keep more transplant centers open.en_US
dc.embargo.terms2020-12-01en_US
dc.format.mimetypeapplication/pdfen_US
dc.identifier.citationMildebrath, David T.K.. "Optimizing Waitlist Composition from the Transplant Center's Perspective." (2018) Master’s Thesis, Rice University. <a href="https://hdl.handle.net/1911/105883">https://hdl.handle.net/1911/105883</a>.en_US
dc.identifier.urihttps://hdl.handle.net/1911/105883en_US
dc.language.isoengen_US
dc.rightsCopyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.en_US
dc.subjectOrgan Transplantationen_US
dc.subjectMathematical Programmingen_US
dc.subjectOperations Researchen_US
dc.titleOptimizing Waitlist Composition from the Transplant Center's Perspectiveen_US
dc.typeThesisen_US
dc.type.materialTexten_US
thesis.degree.departmentComputational and Applied Mathematicsen_US
thesis.degree.disciplineEngineeringen_US
thesis.degree.grantorRice Universityen_US
thesis.degree.levelMastersen_US
thesis.degree.nameMaster of Artsen_US
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