Using Self-Organizing Maps to discover functional relationships of brain areas from fMRI images

dc.contributor.advisorMerenyi, Erzsebeten_US
dc.contributor.committeeMemberKelly, Kevin F.en_US
dc.contributor.committeeMemberRobinson, Jacob T.en_US
dc.contributor.committeeMemberGrossman, Roberten_US
dc.contributor.committeeMemberKarmonik, Christofen_US
dc.creatorO'Driscoll, Patricken_US
dc.date.accessioned2014-10-03T14:52:01Zen_US
dc.date.available2014-10-03T14:52:01Zen_US
dc.date.created2014-05en_US
dc.date.issued2014-04-23en_US
dc.date.submittedMay 2014en_US
dc.date.updated2014-10-03T14:52:01Zen_US
dc.description.abstractThis thesis combines a Conscious Self-Organizing Map (SOM) with an interactive clustering method to analyze functional Magnetic Resonance Imaging (fMRI) data to produce improved brain maps compared to maps produced at The Methodist Hospital and in the literature focusing on similar problems. My new maps exhibit an increased level of symmetry, contiguity, coincidence with functional region, and more complete mapping of functional regions. The examined fMRI data contains brain activations of a subject repeatedly executing willed motion in response to a visual stimulus. Clustering the data from this experiment first determines the optimal preprocessing steps for cluster extraction, and second proves that the Conscious SOM provides a valid brain map that identifies interacting brain regions during the sequence of willed motion. I determined that the geometric rectification, motion correction, temporal smoothing, and normalization preprocessing steps facilitate the best clustering.en_US
dc.format.mimetypeapplication/pdfen_US
dc.identifier.citationO'Driscoll, Patrick. "Using Self-Organizing Maps to discover functional relationships of brain areas from fMRI images." (2014) Master’s Thesis, Rice University. <a href="https://hdl.handle.net/1911/77381">https://hdl.handle.net/1911/77381</a>.en_US
dc.identifier.urihttps://hdl.handle.net/1911/77381en_US
dc.language.isoengen_US
dc.rightsCopyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.en_US
dc.subjectSOMen_US
dc.subjectFunctional magnetic resonance imaging (fMRI)en_US
dc.subjectBrain mapen_US
dc.subjectSelf-organizing mapsen_US
dc.subjectClusteringen_US
dc.titleUsing Self-Organizing Maps to discover functional relationships of brain areas from fMRI imagesen_US
dc.typeThesisen_US
dc.type.materialTexten_US
thesis.degree.departmentApplied Physicsen_US
thesis.degree.disciplineNatural Sciencesen_US
thesis.degree.grantorRice Universityen_US
thesis.degree.levelMastersen_US
thesis.degree.nameMaster of Scienceen_US
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