Magnetoelectric Materials for Wireless Battery-free Bioelectronics

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dc.contributor.advisorRobinson, Jacob Ten_US
dc.creatorChen, Joshua Cen_US
dc.date.accessioned2023-08-09T19:17:26Zen_US
dc.date.created2023-05en_US
dc.date.issued2023-04-18en_US
dc.date.submittedMay 2023en_US
dc.date.updated2023-08-09T19:17:27Zen_US
dc.description.abstractBioelectronic medicine enables the treatment of a myriad of diseases that are often unresponsive to traditional therapeutics. While existing state-of-the-art devices such as the pacemaker or deep brain stimulator have been used for several decades in the clinic, the core technology has not changed since they were first invented. Major limitations for these technologies is that they have large device footprints which leads to more invasive surgeries, higher risks of site infections, post-operative complications, and the need for repeat surgeries. In this dissertation, I describe the advancement of next generation implantable bioelectronics, moving toward battery-free implants by leveraging a new branch of wireless power transfer technology. These battery-free bioelectronics take advantage of magnetoelectric materials to harvest electrical energy from an applied magnetic field, miniaturizing implants from the centimeter scale down to the millimeter regime. I demonstrate the first digitally programmable, wireless, endovascular peripheral nerve stimulator, called the MagnetoElectric BioImplanT (ME-BIT), which couples CMOS and ME materials. I further miniaturize the neural interface and develop a material based neural stimulator called the Magnetoelectric Nonlinear Metamaterial (MNM) which demonstrates the first nonlinear magnetoelectric coupling coefficient and we take advantage of this engineered metamaterial to directly stimulate excitable cells. Overall, magnetoelectrics hold significant promise for scalable next generation implantable bioelectronics for a variety of different applications.en_US
dc.embargo.lift2023-11-01en_US
dc.embargo.terms2023-11-01en_US
dc.format.mimetypeapplication/pdfen_US
dc.identifier.citationChen, Joshua C. "Magnetoelectric Materials for Wireless Battery-free Bioelectronics." (2023) Diss., Rice University. <a href="https://hdl.handle.net/1911/115178">https://hdl.handle.net/1911/115178</a>.en_US
dc.identifier.urihttps://hdl.handle.net/1911/115178en_US
dc.language.isoengen_US
dc.rightsCopyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.en_US
dc.subjectWirelessen_US
dc.subjectBioelectronicsen_US
dc.subjectNeural Engineeringen_US
dc.subjectMetamaterialsen_US
dc.subjectMagenetoelectricen_US
dc.titleMagnetoelectric Materials for Wireless Battery-free Bioelectronicsen_US
dc.typeThesisen_US
dc.type.materialTexten_US
thesis.degree.departmentBioengineeringen_US
thesis.degree.disciplineEngineeringen_US
thesis.degree.grantorRice Universityen_US
thesis.degree.levelDoctoralen_US
thesis.degree.nameDoctor of Philosophyen_US
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