Snapshot Hyperspectral Imaging for Complete Fundus Oximetry

Simple item page
dc.contributor.advisorTkaczyk, Tomasz S
dc.creatorDwight, Jason G
dc.date.accessioned2017-08-02T14:50:16Z
dc.date.available2017-11-01T05:01:07Z
dc.date.created2017-05
dc.date.issued2017-04-21
dc.date.submittedMay 2017
dc.date.updated2017-08-02T14:50:16Z
dc.description.abstractIn this work, a snapshot hyperspectral imager capable of tuning its average spectral resolution from 22.7 nm to 13.9 nm in a single integrated form is presented. The principle of this system will enable future snapshot systems to dynamically adapt to a wide range of imaging situations. Additionally, the system overcomes datacube size limitations imposed by detector array size limits. The work done in this thesis also advances oximetry of the retina using data collected by the Image Mapping spectrometer (IMS), a snapshot spectrometer. Hyperspectral images of the retina are acquired, and oximetry of individual vessels in four diseased eyes is presented. Further, oximetry of the entire fundus is performed using a novel algorithm with data collected with the IMS. We present oxyhemoglobin concentration maps of the eye and demonstrate oxygen sensitivity of the maps by comparing normal and diseased eyes. The aim of this work is to advance the general capabilities of snapshot hyperspectral imagers and to advance the integration of retinal oximetry into the standard ophthalmology instrument repertoire.
dc.embargo.terms2017-11-01
dc.format.mimetypeapplication/pdf
dc.identifier.citationDwight, Jason G. "Snapshot Hyperspectral Imaging for Complete Fundus Oximetry." (2017) Diss., Rice University. <a href="https://hdl.handle.net/1911/96157">https://hdl.handle.net/1911/96157</a>.
dc.identifier.urihttps://hdl.handle.net/1911/96157
dc.language.isoeng
dc.rightsCopyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.
dc.subjectOximetry
dc.subjectRetina
dc.subjectSnapshot
dc.subjectHyperspectral
dc.subjectTunability
dc.titleSnapshot Hyperspectral Imaging for Complete Fundus Oximetry
dc.typeThesis
dc.type.materialText
thesis.degree.departmentBioengineering
thesis.degree.disciplineEngineering
thesis.degree.grantorRice University
thesis.degree.levelDoctoral
thesis.degree.majorImaging
thesis.degree.nameDoctor of Philosophy
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
DWIGHT-DOCUMENT-2017.pdf
Size:
4.98 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 2 of 2
No Thumbnail Available
Name:
PROQUEST_LICENSE.txt
Size:
5.83 KB
Format:
Plain Text
Description:
Download
No Thumbnail Available
Name:
LICENSE.txt
Size:
2.6 KB
Format:
Plain Text
Description:
Download
Collections
Rice University Electronic Theses and Dissertations