Manifold Approximating Graph Interpolation of Cardiac Local Activation Time

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dc.contributor.advisorAazhang, Behnaam
dc.creatorHellar, Jennifer
dc.date.accessioned2021-12-06T20:11:17Z
dc.date.available2021-12-06T20:11:17Z
dc.date.created2021-12
dc.date.issued2021-12-01
dc.date.submittedDecember 2021
dc.date.updated2021-12-06T20:11:17Z
dc.description.abstractLocal activation time (LAT) mapping of cardiac chambers is vital for targeted treatment of cardiac arrhythmias in catheter ablation procedures. Current methods require many LAT observations for an accurate interpolation of the LAT signal extracted from intracardiac electrograms (EGMs). Additionally, conventional performance metrics do not accurately measure the quality of interpolated maps. We propose, first, a novel graph-based method for spatial interpolation of the LAT signal with respect to the manifold; second, a realistic sub-sampling protocol for LAT interpolation testing; and third, a new color-based metric for evaluation of interpolation quality that quantifies perceived differences in LAT maps. We evaluate our approach on a dataset consisting of seven LAT maps from four patients obtained by the CARTO electroanatomic mapping system during premature ventricular complex (PVC) ablations. Our results show excellent accuracy for relatively few observations, achieving on average 6% lower error than state-of-the-art techniques for only 100 observations.
dc.format.mimetypeapplication/pdf
dc.identifier.citationHellar, Jennifer. "Manifold Approximating Graph Interpolation of Cardiac Local Activation Time." (2021) Master’s Thesis, Rice University. <a href="https://hdl.handle.net/1911/111768">https://hdl.handle.net/1911/111768</a>.
dc.identifier.urihttps://hdl.handle.net/1911/111768
dc.language.isoeng
dc.rightsCopyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.
dc.subjectablation
dc.subjectlocal activation time
dc.subjectgraph signal processing
dc.subjectsemi-supervised learning
dc.titleManifold Approximating Graph Interpolation of Cardiac Local Activation Time
dc.typeThesis
dc.type.materialText
thesis.degree.departmentElectrical and Computer Engineering
thesis.degree.disciplineEngineering
thesis.degree.grantorRice University
thesis.degree.levelMasters
thesis.degree.nameMaster of Science
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