The role of calcium in light adaptation of the crayfish photoreceptor

dc.contributor.advisorGlantz, Raymon M.en_US
dc.creatorSon, Edward Mun-Songen_US
dc.date.accessioned2009-06-03T23:52:23Zen_US
dc.date.available2009-06-03T23:52:23Zen_US
dc.date.issued1992en_US
dc.description.abstractAs previously shown in many other photoreceptors, during prolonged exposure to light, receptor sensitivity (mv/photon catch) declines and the speed of the response (rate of depolarization and rate of repolarization) increases. The functional significance of internal and external calcium in these changes were examined in the crayfish. We show that the response time characteristics depend significantly on the internal calcium level, whereas sensitivity appears to depend on the extracellular calcium. The effect of BAPTA, a calcium chelator, within the photoreceptor was to slow the response kinetics without changing sensitivity. We also examined the role of potassium channel blockers in accounting for BAPTA's effect. Although these blockers displayed similar effects to that of BAPTA, the data fail to provide irrefutable evidence that calcium works through the activation or the deactivation of K$\sp{+}$ conductances alone. Probably (even exclusively), internal calcium also affects the transduction process that precedes the channels openings.en_US
dc.format.extent35 p.en_US
dc.format.mimetypeapplication/pdfen_US
dc.identifier.callnoThesis Biochem. 1992 Sonen_US
dc.identifier.citationSon, Edward Mun-Song. "The role of calcium in light adaptation of the crayfish photoreceptor." (1992) Master’s Thesis, Rice University. <a href="https://hdl.handle.net/1911/13600">https://hdl.handle.net/1911/13600</a>.en_US
dc.identifier.urihttps://hdl.handle.net/1911/13600en_US
dc.language.isoengen_US
dc.rightsCopyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.en_US
dc.subjectNeurosciencesen_US
dc.titleThe role of calcium in light adaptation of the crayfish photoreceptoren_US
dc.typeThesisen_US
dc.type.materialTexten_US
thesis.degree.departmentBiochemistry and Cell Biologyen_US
thesis.degree.disciplineNatural Sciencesen_US
thesis.degree.grantorRice Universityen_US
thesis.degree.levelMastersen_US
thesis.degree.nameMaster of Scienceen_US
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