Gauss Integral as a structural descriptor of proteins

dc.contributor.advisorMa, Jianpengen_US
dc.creatorMei, Yuanen_US
dc.date.accessioned2018-12-03T18:31:53Zen_US
dc.date.available2018-12-03T18:31:53Zen_US
dc.date.issued2008en_US
dc.description.abstractProtein is one of the most important macromolecules in structural biology. Its three-dimensional structure is uniquely determined by its amino-acid sequence. Due to large number of degrees of freedom and enormous diversity, it is important to seek universal geometric measures to describe the overall structure of proteins. Gauss Integral and its related quantities are shown to be capable of describing important features of protein structures on different levels. On the atomic level, the Gauss Integral provides a simple measure to illustrate the orientational relation between different atom groups. It can be viewed as a generalization of the Ramachandran map, and it also reveals several novel relations between backbone atoms. On the other hand, Gauss Integrals can be treated as a set of collective quantities that capture the overall shape of proteins. By comparing the values of Gauss Integrals, different types of proteins can be classified in accordance with the results of manually classified structure database.en_US
dc.format.extent55 ppen_US
dc.identifier.callnoTHESIS PHYS. 2008 MEIen_US
dc.identifier.citationMei, Yuan. "Gauss Integral as a structural descriptor of proteins." (2008) Master’s Thesis, Rice University. <a href="https://hdl.handle.net/1911/103615">https://hdl.handle.net/1911/103615</a>.en_US
dc.identifier.digital304510883en_US
dc.identifier.urihttps://hdl.handle.net/1911/103615en_US
dc.language.isoengen_US
dc.rightsCopyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.en_US
dc.subjectBiophysicsen_US
dc.subjectBiological sciencesen_US
dc.titleGauss Integral as a structural descriptor of proteinsen_US
dc.typeThesisen_US
dc.type.materialTexten_US
thesis.degree.departmentPhysicsen_US
thesis.degree.disciplineNatural Sciencesen_US
thesis.degree.grantorRice Universityen_US
thesis.degree.levelMastersen_US
thesis.degree.nameMaster of Scienceen_US
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