The iron sulfides (FeS) constitute a diverse group of solids and dissolved complexes, many of which play critical roles in the natural system, such as marine sedimentation and biochemical processes. It has also become a significant problem in various industrial processes, such as water and wastewater treatment, metal equipment corrosion by hydrogen sulfide, and oil and gas production. Extensive studies have been done in the past century to better understand, predict, and control the sulfide mineral precipitation, of which the importance can never be overstated. In this work, a systematic study of the solubility, precipitation kinetics, and the chemical dispersion control of iron sulfide is conducted to better understand iron sulfide scale prediction and control in industrial processes.