Boron nitride nanomaterials are an exciting and understudied class of materials with enticing properties for a wide range of applications. They’re extremely lightweight and strong, with high thermal and chemical stability, and a wide bandgap that makes them electrically insulating and transparent to visible light. This unique set of properties makes them exceptional candidates for application in fields ranging from space exploration to drug delivery; however, obtainment of these advanced applications still requires researchers to overcome some large obstacles. Chief among them is the amphiphobic nature of the materials, which makes them difficult to work with in liquid-phase processes that are key to material processing and biomedical applications alike. This thesis investigates how to produce uniform dispersions of boron nitride nanomaterials in aqueous solution, and then, probes how the materials behave within these dispersions using single molecule diffusion studies.