Browsing by Author "Zhang, Xiujun"
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Item Bacteria and method for synthesizing fatty acids(2019-11-05) San, Ka-yiu; Li, Mai; Zhang, Xiujun; Rice University; United States Patent and Trademark OfficeThere is provided a recombinant bacterium comprising at least one overexpressed acyl-ACP thioesterase gene, and wherein at least one gene from the tricarboxylic acid cycle or glycolysis or both is inactivated. There is also provided a method for producing fatty acids, said method comprising culturing bacteria comprising at least one overexpressed acyl-ACP thioesterase gene in a growth medium in a container having walls; allowing said bacteria to secrete fatty acids; and collecting said fatty acids. Acid supplementation is also shown to increase productivity.Item Bacteria and method for synthesizing fatty acids(2016-04-12) San, Ka-yiu; Li, Mai; Zhang, Xiujun; Rice University; United States Patent and Trademark OfficeThere is provided a recombinant bacterium comprising at least one overexpressed acyl-ACP thioesterase gene, and wherein at least one gene from the tricarboxylic acid cycle or glycolysis or both is inactivated. There is also provided a method for producing fatty acids, said method comprising culturing bacteria comprising at least one overexpressed acyl-ACP thioesterase gene in a growth medium in a container having walls; allowing said bacteria to secrete fatty acids; and collecting said fatty acids. Acid supplementation is also shown to increase productivity.