Browsing by Author "Yaszemski, Michael J."

Now showing 1 - 5 of 5
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    Biodegradable poly (propylene fumarate) networks cross linked with poly (propylene fumarate) -diacrylate macromers
    (2004-07-06) He, Shulin; Yaszemski, Michael J.; Mikos, Antonios G.; Rice University; United States Patent and Trademark Office
    A network consisting essentially of poly(propylene fumarate) cross linked with diacrylate and a method for making same.
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    Biodegradable poly(propylene fumarate) networks cross linked with poly(propylene fumarate)-diacrylate macromers
    (2002-07-23) He, Shulin; Yaszemski, Michael J.; Mikos, Antonios G.; Rice University; United States Patent and Trademark Office
    A network consisting essentially of poly(propylene fumarate) cross linked with diacrylate and a method for making same.
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    Bone replacement compound comprising poly(polypropylene fumarate)
    (2000-09-26) Peter, Susan J.; Yaszemski, Michael J.; Mikos, Antonios G.; Rice University; United States Patent and Trademark Office
    A method for controlling the gel point of a bone cement containing poly(polypropylene fumarate), a cross-linking monomer, an initiator, an inorganic filler, and a radical initiator. The gel point is controlled by varying the molecular weight of the poly(polypropylene fumarate) while maintaining the weight average molecular weight (Mw) of the poly(polypropylene fumarate) above 2000 and the polydispersity index of the poly(polypropylene fumarate) below 2. In a preferred embodiment, the molecular weight of the poly(polypropylene fumarate) greater than 4000, and more preferably greater than 5000.
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    Method of making poly(propylene fumarate-coethylene oxide)
    (1997-07-01) Suggs, Laura J.; Payne, Richard G.; Yaszemski, Michael J.; Mikos, Antonios G.; Rice University; United States Patent and Trademark Office
    A biodegradable block copolymer made from the transesterfication of a poly(propylene fumarate) prepolymer and a poly(ethylene oxide) prepolymer. The block copolymer poly(propylene fumarate -co- ethylene oxide) is capable of crosslinking at body temperature. Crosslinking requires an appropriate crosslinking monomer and an initiator. The biodegradable block copolymer has utility as a vascular implant became it can be injected as a fluid into the vascular system and crosslinked in situ.
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    Poly(Propylene Fumarate) cross linked with Poly(Ethylene Glycol)
    (2002-05-07) He, Shulin; Yaszemski, Michael J.; Mikos, Antonios G.; Rice University; United States Patent and Trademark Office
    New injectable, in situ crosslinkable biodegradable polymer composites comprise poly(propylene fumarate) (PPF), poly(ethylene glycol)-dimethacrylate (PEG-DMA), an, optionally, β-tricalcium phosphate (β-TCP). A method for controlling the crosslinking characteristics of the composites, including the maximum crosslinking temperature and the gel point, as well as the properties of the cross linked composites such as the compressive strength and modulus and the water holding capacity, is disclosed.