Browsing by Author "Perepelitsa, Misha"

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    Breakdown of Boltzmann-type models for the alignment of self-propelled rods
    (Elsevier, 2024) Murphy, Patrick; Perepelitsa, Misha; Timofeyev, Ilya; Lieber-Kotz, Matan; Islas, Brandon; Igoshin, Oleg A.; Bioengineering; Biosciences; Chemistry; Center for Theoretical Biological Physics
    Studies in the collective motility of organisms use a range of analytical approaches to formulate continuous kinetic models of collective dynamics from rules or equations describing agent interactions. However, the derivation of these kinetic models often relies on Boltzmann’s “molecular chaos” hypothesis, which assumes that correlations between individuals are short-lived. While this assumption is often the simplest way to derive tractable models, it is often not valid in practice due to the high levels of cooperation and self-organization present in biological systems. In this work, we illustrated this point by considering a general Boltzmann-type kinetic model for the alignment of self-propelled rods where rod reorientation occurs upon binary collisions. We examine the accuracy of the kinetic model by comparing numerical solutions of the continuous equations to an agent-based model that implements the underlying rules governing microscopic alignment. Even for the simplest case considered, our comparison demonstrates that the kinetic model fails to replicate the discrete dynamics due to the formation of rod clusters that violate statistical independence. Additionally, we show that introducing noise to limit cluster formation helps improve the agreement between the analytical model and agent simulations but does not restore the agreement completely. These results highlight the need to both develop and disseminate improved moment-closure methods for modeling biological and active matter systems.
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    Mean-field model for nematic alignment of self-propelled rods
    (American Physical Society, 2022) Perepelitsa, Misha; Timofeyev, Ilya; Murphy, Patrick; Igoshin, Oleg A.; Bioengineering; Biosciences; Chemistry; Center for Theoretical Biological Physics
    Self-propelled rods are a facet of the field of active matter relevant to many physical systems ranging in scale from shaken granular media and bacterial alignment to the flocking dynamics of animals. In this paper we develop a model for nematic alignment of self-propelled rods interacting through binary collisions. We avoid phenomenological descriptions of rod interaction in favor of rigorously using a set of microscopic-level rules. Under the assumption that each collision results in a small change to a rod's orientation, we derive the Fokker-Planck equation for the evolution of the kinetic density function. Using analytical and numerical methods, we study the emergence of the nematic order from a homogeneous, uniform steady state of the mean-field equation. We compare the level of orientational noise needed to destabilize this nematic order and compare our results to an existing phenomenological model that does not explicitly account for the physical collisions of rods. We show the presence of an additional geometric factor in our equations reflecting a reduced collision rate between nearly aligned rods that reduces the level of noise at which nematic order is destroyed, suggesting that alignment that depends on purely physical collisions is less robust.