Browsing by Author "Payne, Richard G."
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Item Method of making poly(propylene fumarate-coethylene oxide)(1997-07-01) Suggs, Laura J.; Payne, Richard G.; Yaszemski, Michael J.; Mikos, Antonios G.; Rice University; United States Patent and Trademark OfficeA biodegradable block copolymer made from the transesterfication of a poly(propylene fumarate) prepolymer and a poly(ethylene oxide) prepolymer. The block copolymer poly(propylene fumarate -co- ethylene oxide) is capable of crosslinking at body temperature. Crosslinking requires an appropriate crosslinking monomer and an initiator. The biodegradable block copolymer has utility as a vascular implant became it can be injected as a fluid into the vascular system and crosslinked in situ.