Browsing by Author "Madden, Dean R."

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    Hybrid organic-inorganic inhibitors of a PDZ-peptide interaction that regulates CFTR endocytic fate
    (Wiley-VCH Verlag, 2012) Kundu, Rituparna; Cushing, Patrick R.; Popp, Brian V.; Zhao, Yu; Madden, Dean R.; Ball, Zachary T.
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    Small molecule conjugates with dimetal species for protein inhibition
    (2015-06-02) Ball, Zachary T.; Kundu, Rituparna; Popp, Brian V.; Madden, Dean R.; Cushing, Patrick R.; Rice University; Trustees of Dartmouth College; United States Patent and Trademark Office
    Methods for targeting a protein by providing an inhibitor covalently linked to a rhodium(II) complex, introducing the inhibitor to the target protein and allowing the inhibitor and protein to interact. The rhodium(II) complex covalently linked to the inhibitor binds the target protein both inorganically and organically and forms stabilizing secondary contacts between the rhodium(II) complex and the protein.