Browsing by Author "Li, Mai"

Now showing 1 - 3 of 3
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    Bacteria and method for synthesizing fatty acids
    (2019-11-05) San, Ka-yiu; Li, Mai; Zhang, Xiujun; Rice University; United States Patent and Trademark Office
    There is provided a recombinant bacterium comprising at least one overexpressed acyl-ACP thioesterase gene, and wherein at least one gene from the tricarboxylic acid cycle or glycolysis or both is inactivated. There is also provided a method for producing fatty acids, said method comprising culturing bacteria comprising at least one overexpressed acyl-ACP thioesterase gene in a growth medium in a container having walls; allowing said bacteria to secrete fatty acids; and collecting said fatty acids. Acid supplementation is also shown to increase productivity.
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    Bacteria and method for synthesizing fatty acids
    (2016-04-12) San, Ka-yiu; Li, Mai; Zhang, Xiujun; Rice University; United States Patent and Trademark Office
    There is provided a recombinant bacterium comprising at least one overexpressed acyl-ACP thioesterase gene, and wherein at least one gene from the tricarboxylic acid cycle or glycolysis or both is inactivated. There is also provided a method for producing fatty acids, said method comprising culturing bacteria comprising at least one overexpressed acyl-ACP thioesterase gene in a growth medium in a container having walls; allowing said bacteria to secrete fatty acids; and collecting said fatty acids. Acid supplementation is also shown to increase productivity.
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    Bacteria and method for synthesizing fatty acids
    (2017-03-21) San, Ka-yiu; Li, Mai; Rice University; United States Patent and Trademark Office
    The present invention discloses a process for increasing the production of free fatty acids at high yield (close to maximum theoretical yield), with various fatty acid compositions and various percentage of fatty acids accumulated intracellularly. This invention will enable the efficient production of other products derived from free fatty acids and/or products that can be branched out from the fatty acid synthesis pathways.