Browsing by Author "Kasper, Kurtis F."

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    Combined space maintenance and bone regeneration system for the reconstruction of large osseous defects
    (2017-01-03) Mikos, Antonios G.; Wong, Mark E.; Young, Simon W.; Kretlow, James D.; Shi, Meng; Kasper, Kurtis F.; Spicer, Patrick; Rice University; United States Patent and Trademark Office
    Systems, methods and compositions useful for treatment of traumatic bone injuries are provided. In one embodiment, a bone reconstruction system comprising a space maintaining composition comprising porous polymethylmethacrylate; and an osseous generating construct comprising a polymethylmethacrylate chamber that comprises one or more osseous generating materials is provided. Associated compositions and methods are also provided.
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    Injectable hydrogels
    (2016-03-15) Mikos, Antonios G.; Kasper, Kurtis F.; Ekenseair, Adam K.; Vo, Tiffany N.; Boere, Kristel W.M.; Touchet, Tyler J.; Rice University; United States Patent and Trademark Office
    The present disclosure generally relates to injectable compositions. More particularly, the present disclosure relates to injectable, thermogelling hydrogels and associated methods. In one embodiment, the present disclosure provides for a composition comprising a poly(N-isopropylacrylamide)-based macromer and a polyamidoamine-based macromer.