Browsing by Author "Karsenty, Gerard"

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    Cytokine-bisphosphonate conjugates
    (2025-04-22) Karsenty, Gerard; Berger, Julian; Xiao, Han; Rice University; The Trustees of Columbia University in the City of New York; United States Patent and Trademark Office
    Cytokine-bisphosphonate conjugates and methods of use thereof in muscle functions.
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    Methods, compositions and uses thereof for reversing sarcopenia
    (2025-02-04) Karsenty, Gerard; Berger, Julian; Xiao, Han; Rice University; The Trustees of Columbia University in the City of New York; United States Patent and Trademark Office
    Exemplary methods, compositions and uses thereof can be provided for preventing, reducing and/or treating loss of muscle function. In particular, e.g., it is possible to administer to a subject a pharmaceutical composition comprising a therapeutically effective amount of an agent that enhances Interleukin-6 (IL) release during exercise, and optionally a pharmaceutically acceptable carrier or excipient.