Browsing by Author "Hartgerink, Jeffrey Dale"

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    Multidomain peptides for promoting angiogenesis
    (2016-12-27) Hartgerink, Jeffrey Dale; Kumar, Vivek Ashok; Rice University; United States Patent and Trademark Office
    The present disclosure provides a composition comprising a multi-domain peptide capable of self-assembly into a nanofibrous hydrogel structure capable of stimulating a robust angiogenic response. In one embodiment, the composition comprises a short 15 amino acid VEGF-165 peptide mimic conjugated to a 16 amino acid multidomain peptide. A method for promoting angiogenesis and/or treating ischemic wounds in a subject is also provided.