Browsing by Author "Goetz, Christopher G."

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    Fatigue in Parkinson's disease: report from a mutidisciplinary symposium
    (Nature Publishing Group, 2016) Friedman, Joseph H.; Beck, James C.; Chou, Kelvin L.; Clark, Gracia; Fagundes, Christopher P.; Goetz, Christopher G.; Herlofson, Karen; Kluger, Benzi; Krupp, Lauren B.; Lang, Anthony E.; Lou, Jao-Shin; Marsh, Laura; Newbould, Anne; Weintraub, Daniel
    Fatigue is a severe problem for many people living with Parkinson's disease (PD). Best estimates suggest that more than 50% of patients experience this debilitating symptom. Little is known about its etiology or treatment, making the understanding of fatigue a true unmet need. As part of the Parkinson's Disease Foundation Community Choice Research Program, patients, caregivers, and scientists attended a symposium on fatigue on 16 and 17 October 2014. We present a summary of that meeting, reviewing what is known about the diagnosis and treatment of fatigue, its physiology, and what we might learn from multiple sclerosis (MS), depression, and cancer-disorders in which fatigue figures prominently too. We conclude with focused recommendations to enhance our understanding and treatment of this prominent problem in PD.