Browsing by Author "Doty, Nathaniel J."
Now showing 1 - 1 of 1
Results Per Page
Sort Options
Item Multilayered, Hyaluronic Acid-Based Hydrogel Formulations Suitable for Automated 3D High Throughput Drug Screening of Cancer-Stromal Cell Cocultures(Wiley, 2015) Engel, Brian J.; Constantinou, Pamela E.; Sablatura, Lindsey K.; Doty, Nathaniel J.; Carson, Daniel D.; Farach-Carson, Mary C.; Harrington, Daniel Anton; Zarembinski, Thomas I.Validation of a high-throughput compatible 3D hyaluronic acid hydrogel coculture of cancer cells with stromal cells. The multilayered hyaluronic acid hydrogels improve drug screening predictability as evaluated with a panel of clinically relevant chemotherapeutics in both prostate and endometrial cancer cell lines compared to 2D culture.