Briggs, NeimaWeatherhead, JillSastry, K. JagannadhaHotez, Peter J.2017-05-192017-05-192016Briggs, Neima, Weatherhead, Jill, Sastry, K. Jagannadha, et al.. "The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections." <i>PLoS Neglected Tropical Diseases,</i> 10, no. 9 (2016) Public Library of Science: https://doi.org/10.1371/journal.pntd.0004944.https://hdl.handle.net/1911/94290Current iterations of the hygiene hypothesis suggest an adaptive role for helminth parasites in shaping the proper maturation of the immune system. However, aspects of this hypothesis are based on assumptions that may not fully account for realities about human helminth infections. Such realities include evidence of causal associations between helminth infections and asthma or inflammatory bowel disease as well as the fact that helminth infections remain widespread in the United States, especially among populations at greatest risk for inflammatory and autoimmune diseases.engThis is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Journal articlehttps://doi.org/10.1371/journal.pntd.0004944