2015-05-042015-05-042012-06-26San, Ka-Yiu, Chung, Ill-Min and Ahmad, Ateeque, "Natural products from Vinca." Patent US8207313B2. issued 2012-06-26. Retrieved from https://hdl.handle.net/1911/80097.https://hdl.handle.net/1911/80097New and useful compounds C. roseus cultured hairy roots are provided, by Isolating flavone glycosides together with a pharmaceutically acceptable carrier. This is accomplished by immersing powdered the hairy roots in methanol to produce an extract, concentrating the extract, resuspending the extract in water, extracting the compound with organic solvent, and isolating the compound from the organic solvent.14 ppengUtility patentUS8207313B2