Clark, John W., Jr.2009-06-042009-06-041995McMahon, Michael George. "An electrodiffusion model of conduction in nerve fibers." (1995) Master’s Thesis, Rice University. <a href="https://hdl.handle.net/1911/13976">https://hdl.handle.net/1911/13976</a>.https://hdl.handle.net/1911/13976A new membrane model for mammalian nerve fibers has been developed. The membrane model utilizes new characterizations for delayed-rectifier currents, and adds an inwardly-rectifying potassium channel as well as a sodium-potassium pump current. Fits are shown to action potential and I-V data at two different temperatures. The Nernst-Planck electrodiffusion equation was then utilized to derive a linked compartmental model of the unmyelinated mammalian nerve fiber with lumped parameter values. The results from this unmyelinated fiber model were presented and compared to data in the literature. A myelinated nerve axon model is also developed and issues of numerical implementation are discussed.118 p.application/pdfengCopyright is held by the author, unless otherwise indicated. Permission to reuse, publish, or reproduce the work beyond the bounds of fair use or other exemptions to copyright law must be obtained from the copyright holder.ElectronicsElectrical engineeringBiomedical engineeringNeurosciencesBiologyEngineeringThesisTHESIS E.E. 1996 MCMAHON