Zheng, WenjTao, Yizhi Jane2014-10-062014-10-062013Zheng, Wenj and Tao, Yizhi Jane. "Structure and assembly of the influenza A virus ribonucleoprotein complex." <i>FEBS Letters,</i> 587, no. 8 (2013) Elsevier: 1206-1214. http://dx.doi.org/10.1016/j.febslet.2013.02.048.https://hdl.handle.net/1911/77394The genome of influenza A viruses consists of eight segments of single-stranded, negative-sense RNA that are encapsidated as individual rod-shaped ribonucleoprotein complexes (RNPs). Each RNP contains a viral RNA, a viral polymerase and multiple copies of the viral nucleoprotein (NP). Influenza A virus RNPs play important roles during virus infection by directing viral RNA replication and transcription, intracellular transport of the viral RNA, gene reassortment as well as viral genome packaging into progeny particles. As a unique genomic entity, the influenza A virus RNP has been extensively studied since the 1960s. Recently, exciting progress has been made in studying the RNP structure and its assembly, leading to a better understanding of the structural basis of various RNP functions.engThis is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.Journal articleInfluenza A virusRibonucleoprotein complexRNPnucleoproteinNPstructureassemblyhttp://dx.doi.org/10.1016/j.febslet.2013.02.048